Guido Iaccarino Selected Research

G-Protein-Coupled Receptor Kinase 2

11/2020	Role of Endothelial G Protein-Coupled Receptor Kinase 2 in Angioedema.
3/2013	G-protein-coupled receptor kinase 2 and hypertension: molecular insights and pathophysiological mechanisms.
3/2012	GRK2 levels in umbilical arteries of pregnancies complicated by gestational hypertension and preeclampsia.
2/2012	Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis.
5/2011	G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.
4/2011	G protein-coupled receptor kinase 2 in patients with acute myocardial infarction.
12/2009	The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance.
10/2009	G-protein-coupled receptor kinases in cardiovascular conditions: focus on G-protein-coupled receptor kinase 2, a gain in translational medicine.

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Guido Iaccarino Research Topics

Disease

26	Hypertension (High Blood Pressure) 11/2022 - 07/2002
18	Heart Failure 11/2021 - 06/2003
10	Neoplasms (Cancer) 11/2020 - 11/2009
9	COVID-19 07/2022 - 01/2020
9	Insulin Resistance 01/2022 - 12/2009
9	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 10/2009
8	Hypertrophy 11/2015 - 09/2002
5	Cardiotoxicity 01/2019 - 02/2016
5	Cardiomegaly (Heart Hypertrophy) 03/2018 - 11/2004
4	Chronic Renal Insufficiency 11/2022 - 01/2020
4	Mitochondrial Diseases (Mitochondrial Disease) 06/2022 - 10/2013
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2021 - 05/2009
4	Myocardial Infarction 07/2021 - 10/2008
4	Ischemia 07/2012 - 05/2007
3	Stroke (Strokes) 11/2022 - 03/2007
3	Inflammation (Inflammations) 08/2019 - 11/2008
3	Atherosclerosis 01/2017 - 09/2011
2	Fabry Disease (Fabry's Disease) 06/2022 - 01/2021
2	Hyperuricemia 01/2022 - 01/2021
2	Kidney Diseases (Kidney Disease) 01/2022 - 01/2021
2	Heart Diseases (Heart Disease) 11/2021 - 01/2012
2	Noncommunicable Diseases 12/2020 - 01/2020
2	Death (Near-Death Experience) 01/2020 - 09/2010
2	Essential Hypertension 01/2020 - 01/2018
2	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 03/2007
2	Cognitive Dysfunction 01/2019 - 03/2007
2	Diabetes Mellitus 11/2017 - 11/2017
2	Necrosis 02/2016 - 01/2016
2	Hypoxia (Hypoxemia) 07/2012 - 02/2012
2	Coronary Artery Disease (Coronary Atherosclerosis) 05/2012 - 09/2010
2	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 10/2010 - 12/2006
1	Albuminuria 01/2022
1	Gout 01/2022
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 07/2021
1	Thromboembolism 01/2021
1	Cytokine Release Syndrome 12/2020
1	Lung Injury 12/2020
1	Thyroid Neoplasms (Thyroid Cancer) 11/2020
1	Angioedema 11/2020
1	Severe Acute Respiratory Syndrome 04/2020

Drug/Important Bio-Agent (IBA)

10	Uric Acid (Urate)IBA 11/2022 - 01/2020
8	G-Protein-Coupled Receptor Kinase 2IBA 11/2020 - 10/2009
7	Insulin (Novolin)FDA Link 01/2021 - 12/2009
7	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 05/2009
6	Antihypertensive Agents (Antihypertensives)IBA 07/2022 - 12/2006
6	Phosphotransferases (Kinase)IBA 11/2020 - 01/2012
5	DiureticsIBA 11/2022 - 05/2014
5	Adrenergic Agents (Adrenergic Drugs)IBA 01/2018 - 07/2002
5	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2016 - 11/2004
5	Proteins (Proteins, Gene)FDA Link 02/2015 - 03/2007
4	Transcription Factors (Transcription Factor)IBA 03/2019 - 10/2010
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 02/2016
4	Pharmaceutical PreparationsIBA 01/2019 - 11/2017
4	CalciumIBA 03/2018 - 02/2015
4	beta Adrenergic ReceptorsIBA 12/2009 - 07/2002
3	Ethanol (Ethyl Alcohol)IBA 11/2022 - 01/2020
3	LDL CholesterolIBA 11/2022 - 01/2020
3	MicroRNAs (MicroRNA)IBA 07/2022 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 07/2022 - 10/2009
3	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021 - 01/2016
3	CytokinesIBA 03/2019 - 11/2008
3	Calmodulin (Calcium-Dependent Activator Protein)IBA 03/2018 - 01/2015
3	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2017 - 01/2015
3	G-Protein-Coupled Receptor KinasesIBA 11/2015 - 12/2008
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2011 - 07/2002
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 10/2009 - 09/2005
2	alpha-Galactosidase (Beano)IBA 06/2022 - 01/2021
2	CreatinineIBA 01/2022 - 05/2009
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 04/2020
2	Angiotensin Receptor AntagonistsIBA 01/2021 - 04/2020
2	Oxygen (Dioxygen)IBA 01/2021 - 05/2014
2	AntioxidantsIBA 01/2021 - 01/2018
2	Vitamin D FDA LinkGeneric 01/2018 - 01/2017
2	EnzymesIBA 01/2016 - 07/2012
2	Messenger RNA (mRNA)IBA 02/2015 - 03/2007
2	Vasodilator Agents (Vasodilators)IBA 05/2014 - 03/2012
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2014 - 10/2010
2	Atrial Natriuretic Factor (ANF)IBA 05/2012 - 10/2010
1	globotriaosylceramide (globotriosylceramide)IBA 06/2022
1	Triglycerides (Triacylglycerol)IBA 01/2022
1	AlbuminsIBA 01/2022
1	Allopurinol (Remid)FDA LinkGeneric 01/2022
1	glucoraphaninIBA 01/2021
1	CholesterolIBA 01/2021
1	AnkyrinsIBA 01/2021
1	AnticoagulantsIBA 01/2021
1	CurcuminIBA 12/2020
1	BerberineIBA 12/2020
1	QuercetinIBA 12/2020
1	ResveratrolIBA 12/2020
1	GenisteinIBA 12/2020
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 12/2020
1	sulforaphaneIBA 12/2020
1	Butylated Hydroxytoluene (BHT)IBA 11/2020
1	BradykininIBA 11/2020
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 04/2020
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 04/2020

Therapy/Procedure

12	Therapeutics 01/2021 - 12/2006
2	Palliative Care (Palliative Therapy) 12/2020 - 01/2020
1	Patient Readmission 01/2020